The common il1a single nucleotide polymorphism rs17561 is a hypomorphic mutation that significantly reduces interleukin‐1α release from human blood cells

HIGHLIGHTS

  • who: The common IL and colleagues from the University of Cambridge, The Heart and Lung Research Institute, Cambridge, UK have published the paper: The common IL1A single nucleotide polymorphism rs17561 is a hypomorphic mutation that significantly reduces interleukinu20101u03b1 release from human blood cells, in the Journal: (JOURNAL)
  • what: The authors show that rs17561 changes a highly conserved alanine to a serine in the central region of IL-1u03b1 targeted for activation. Although the authors show more S114 IL-1u03b1 is WIGGINS ET AL. retained within activated macrophages . Although the authors show the effect of the . . .

     

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