HIGHLIGHTS
SUMMARY
The constructive function of apoptosis: State of the art Apoptosis can change the mechanical properties of a tissue, leading to its remodeling, a phenomenon named "tissue remodeling" or "apoptotic force" (Toyama et_al, 2008; Monier et_al, 2015). Accumulation of the myosin-II filament in an apoptotic cell induces an increase in tissue tension during leg morphogenesis in Drosophila, resulting in epithelium folding by pulling live adjacent cells together at the same time as apoptotic cell expulsion (Monier et_al, 2015). An apoptotic cell-dependent attractive signal was also demonstrated in mammals (named the "eat-me signal . . .
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