The contextual essentiality of mitochondrial genes in cancer

HIGHLIGHTS

  • who: Luke W. Thomas and Margaret Ashcroft from the Department of Medicine, University of Cambridge, Cambridge, United Kingdom have published the article: The Contextual Essentiality of Mitochondrial Genes in Cancer, in the Journal: (JOURNAL) of 14/04/2021
  • what: Mitochondria are key metabolic and signaling hubs in eukaryotic cells, and are the site of numerous biochemical pathways that support cell viability.

SUMMARY

    MITOCHONDRIA AND CANCER Mitochondria are thought to have arisen from the endosymbiotic fusion of a protobacterium that had evolved the ability to generate chemical energy through oxidative_phosphorylation (OXPHOS), and . . .

     

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