HIGHLIGHTS
- who: Anna Crisford and collaborators from the Centre for Biological Sciences, University of Southampton, Southampton, United Kingdom, Bayer have published the Article: The Cyclooctadepsipeptide Anthelmintic Emodepside Differentially Modulates Nematode, Insect and Human Calcium-Activated Potassium (SLO) Channel Alpha Subunits, in the Journal: (JOURNAL)
- what: To address this knowledge gap, here the authors provide the first cross phyla study on the actions of emodepside, on nematode, insect and human channels. The authors provide mechanistic insight which reveals a differential action of emodepside on the nematode channel, a profound facilitation, which underpins its selective toxicity as an . . .
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