The cytokine il-27 reduces inflammation and protects photoreceptors in a mouse model of retinal degeneration

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  • who: Andrea Nortey from the Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA have published the article: The cytokine IL-27 reduces inflammation and protects photoreceptors in a mouse model of retinal degeneration, in the Journal: (JOURNAL)
  • what: The authors investigated effect of IL-27 in rd10 mouse model of inherited photoreceptor degeneration. The aim of this study is to identify a mechanism of controlling excessive inflammation to promote photoreceptor survival. This analysis demonstrated significant reductions in levels of pro-inflammatory proteins IL-18, IL-12p70 and Ccl22 in . . .

     

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