The cytoplasmic synthesis and coupled membrane translocation of eukaryotic polyphosphate by signal-activated vtc complex

HIGHLIGHTS

• who: Zeyuan Guan from the (UNIVERSITY) have published the Article: The cytoplasmic synthesis and coupled membrane translocation of eukaryotic polyphosphate by signal-activated VTC complex, in the Journal: (JOURNAL) of 14/Oct/2022
• what: The authors report the cryo-electron microscopy structure of signal-activated VTC complex at 3.0 u00c5 resolution. Together with biochemical and cellular studies, the work provides mechanistic insights into the biogenesis of an ancient energy metabolite. The authors first performed in-cell 31P-NMR measurements of polyP in yeast strains to characterize the contribution of each Vtc subunit to vacuolar . . .
  

   

  

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