The dct-/- mouse model to unravel retinogenesis misregulation in patients with albinism

HIGHLIGHTS

  • who: Angu00e8le Tingaud-Sequeira et al. from the Rare Diseases Genetics and Metabolism, INSERM, SBM Department, University of Bordeaux, Molecular Genetics Laboratory, Bordeaux University Hospital, Bordeaux, France have published the article: The Dct-/- Mouse Model to Unravel Retinogenesis Misregulation in Patients with Albinism, in the Journal: Genes 2022, 1164 of 21/06/2022
  • what: The authors investigate the eye phenotype in Dct-/- mice. The authors show that their retinal pigmented epithelium (RPE) is severely hypopigmented from early stages contrasting with the darker melanocytic tissues. DCT encodes included in the study have a moderate cutaneous in . . .

     

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