The death effector domain-associated factor plays distinct regulatory roles in the nucleus and cytoplasm*

HIGHLIGHTS

• who: Lixin Zheng from the (UNIVERSITY) have published the Article: The Death Effector Domain-associated Factor Plays Distinct Regulatory Roles in the Nucleus and Cytoplasm*, in the Journal: (JOURNAL) of March/29,/2001
• how: To search for new molecules that potentially regulate death receptor-mediated apoptosis the authors used the DED domains of procaspase-8 and procaspase-10 as molecular baits to screen hu- DEDAF Regulates DED-mediated Apoptosis man cDNA libraries by the yeast two-hybrid system.

SUMMARY

The machinery that regulates proper oligomerization and autoactivation of procaspase-8 and . . .

 



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