HIGHLIGHTS
SUMMARY
Epidemiologically, approximately 22% of patients who evolved with COVID-19, a critical illness caused by SARS-CoV-2, develop an acute liver injury (Nascimento et_al, 2020a; Nascimento et_al, 2020b). Pre-existing chronic liver diseases strongly correlate with morbidity and mortality (Ahmad et_al, 2021; Liu et_al, 2022). This theory was refuted as evidence-based studies showed no worse prognosis among patients with previous liver pathologies (Guan et_al, 2020; Kulkarni et_al, 2020). Acute liver failure could be caused by drug-induced liver injury, as COVID-19 patients are exposed to extensive pharmacological therapies, and most drugs . . .
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