HIGHLIGHTS
- who: Yohei Masugi from the Division of Diagnostic Pathology, Keio University School of Medicine, Tokyo, Japan have published the research work: The Desmoplastic Stroma of Pancreatic Cancer: Multilayered Levels of Heterogeneity, Clinical Significance, and Therapeutic Opportunities, in the Journal: Cancers 2022, 3293 of /2022/
- what: Preliminary data from this trial have reported decreased FAK activity, as well as reduced intratumoral T_cell infiltration, in paired biopsy specimens from the patients . One of the major reasons for this is the immunosuppressive milieu of the desmoplastic stroma . This study has shown improved gemcitabine efficacy as well as synergy . . .
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