The development and improvement of immunodeficient mice and humanized immune system mouse models

HIGHLIGHTS

  • who: Jiaxuan Chen from the United States University of Manitoba, Canada have published the research work: The development and improvement of immunodeficient mice and humanized immune system mouse models, in the Journal: (JOURNAL)
  • what: In this model, a multilineage humanized immune system can be obtained, and longterm reconstruction can be maintained. This model had obvious shortcomings, such as a low level of human cell reconstruction, unstable development of human T_cells, and short survival time .
  • how: The results showed that T B cells monocytes macrophages and neutrophils were developed to normal human levels in . . .

     

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