HIGHLIGHTS
SUMMARY
Single-cell RNA sequencing (scRNA-seq) provides a powerful tool to reveal the cellular and regulatory landscape of both biological processes and disease progression (Puram et_al, 2017; van Galen et_al, 2019; Welch et_al, 2019). Placenta accreta spectrum disorders (PAS) represent one of the most severe complications during pregnancy (Silver and Branch, 2018; Matsuzaki et_al, 2021). Invasive PAS includes PI and PP (Jauniaux et_al, 2019; Hecht et_al, 2020), which are the major concerns for maternal morbidity and mortality from uterine rupture, catastrophic postpartum hemorrhage, and urinary tract injury (Clark et_al, 2008; Creanga et_al, 2015; Erfani . . .
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