The dna damage response is required for oocyte cyst breakdown and follicle formation in mice

HIGHLIGHTS

  • who: Ana Martínez-Marchal and collaborators from the Universitat Autònoma de Barcelona, Cerdanyola Vallès, Spain have published the Article: The DNA damage response is required for oocyte cyst breakdown and follicle formation in mice, in the Journal: (JOURNAL) of February/12,/2020
  • what: Based upon these data the authors propose that the CHK1- and CHK2-dependent DDR controls the number of oocytes and is required to properly break down oocyte cysts and form follicles in mammals. The authors propose CHK2 may participate in the surveillance mechanisms that control the progression of DSB . . .

     

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