The double-faceted role of leucine-rich repeat kinase 2 in the immunopathogenesis of parkinson`s disease

HIGHLIGHTS

  • who: Yu Tang from the Department Geriatrics, Xiangya, South, China, Research Center, Xiangya have published the research: The Double-Faceted Role of Leucine-Rich Repeat Kinase 2 in the Immunopathogenesis of Parkinson`s Disease, in the Journal: (JOURNAL)

SUMMARY

    As one of the most sophisticated organs, the brain exists extensive bidirectional communication between resident immune cells with the peripheral immune system, the disruption of which could lead to cognitive and behavioral disorders (Filiano et_al, 2015; Louveau et_al, 2015; Kipnis, 2016). Functional alterations associated with pathogenic LRRK2 mutations include, but are not limited to . . .

     

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