The dynamic localization of cytoplasmic dynein in neurons is driven by kinesin-1

HIGHLIGHTS

• who: Alison E. Twelvetrees from the Department University of USA have published the article: The Dynamic Localization of Cytoplasmic Dynein in Neurons Is Driven by Kinesin-1, in the Journal: (JOURNAL)
• what: The authors demonstrate that the outward transport of from soma to axon terminal is driven by direct interactions with the anterograde motor kinesin-1. developing neurons the authors find that dynamically cycles between neurites kinesin-1 and accumulating the nascent axon coincident with axon established axons is constantly transported down the axon at slow axonal transport speeds; inhibition of the interaction effectively blocks . . .
  

   

  

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