HIGHLIGHTS
- who: Ilaria Zuliani from the Department of Biochemical Sciences "ARossi Fanelli", Laboratory affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Sapienza University of Rome,Aldo Moro, Rome, Italy have published the research work: The Dysregulation of OGT/OGA Cycle Mediates Tau and APP Neuropathology in Down Syndrome, in the Journal: (JOURNAL)
- what: The authors demonstrate the disruption of O-GlcNAcylation homeostasis as an effect of altered OGT and OGA regulatory mechanism and confirm the relevance of O-GlcNAcylation in the appearance of AD hallmarks in the brain of a murine model of DS. The authors . . .
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