HIGHLIGHTS
- who: Susann Schweiger from the (UNIVERSITY) have published the research: The E3 Ubiquitin Ligase MID1 Catalyzes Ubiquitination and Cleavage of Fu, in the Journal: (JOURNAL) of November/14,/2014
- what: The authors show that human Fu controls the subcellular localization and transcriptional activity of GLI3 in cancer cell lines. In confirmation of these data, the authors show here polyubiquitination of Fu, which increases after proteasomal inhibition. The authors show here that the Fu protein is cleaved into shorter protein fragments. The authors show here that ubiquitination of Fu mediates its proteasomal cleavage, forming a fragment . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.