HIGHLIGHTS
- who: Ziyi Zhao and collaborators from the Department of Gastrointestinal Surgery, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China have published the research work: The Effect of Oxidative Phosphorylation on Cancer Drug Resistance, in the Journal: Cancers 2023, 15, x FOR PEER REVIEW of 22/Dec/2022
SUMMARY
Multiple investigators later found that cancer cells carry functional mitochondria and show upregulated OXPHOS activity following treatment with anticancer drugs. Cancer cells show enhanced mitochondrial OXPHOS mediated by the activation of several oncogenic signaling pathways. In hematologic malignancies, cancer stem_cells (CSCs) display metabolic . . .
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