The effect of tacrolimus-induced toxicity on metabolic profiling in target tissues of mice

HIGHLIGHTS

  • who: Dadi Xie from the (UNIVERSITY) have published the article: The effect of tacrolimus-induced toxicity on metabolic profiling in target tissues of mice, in the Journal: (JOURNAL)
  • what: The study showed significant changes in FBG, Crea, urea and ALT in Tac group , suggesting that the Tac displayed a drug toxicity in the major target organs. The study assessed the metabolic alterations of Tac-induced lung toxicity, and showed marked elevations in the levels of L-lactic acid, L-5-oxoproline, L-threonine, and phosphorylethanolamine in the Tac mice, relative to controls.

SUMMARY . . .

 

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