The effects of hexabromocyclododecane on the transcriptome and hepatic enzyme activity in three human heparg-based models

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  • who: Susana Proenu00e7a from the Department of, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, the Netherlands have published the research work: The effects of hexabromocyclododecane on the transcriptome and hepatic enzyme activity in three human HepaRG-based models, in the Journal: (JOURNAL)
  • what: Given the ambiguous effects of HBCD exposure in HepG2 and the lack of data regarding HBCD effects on T4 hepatic metabolism in human cell systems, this study aims to assess HBCD effects on human hepatic gene_expression and activity of enzymes related to PXR inducu00ad tion and T4 clearance using more hepatic . . .

     

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