The effects of inhibition and sirna knockdown of collagen-binding integrins on human umbilical vein endothelial cell migration and tube formation

HIGHLIGHTS

• who: Emma J. Hunter from the DepartmentUniversity of have published the research: The effects of inhibition and siRNA knockdown of collagen-binding integrins on human umbilical vein endothelial cell migration and tube formation, in the Journal: Scientific Reports Scientific Reports
• what: The work describes novel expression of the chondrocyte-associated integrin, u03b110u03b21, in HUVECs at the mRNA transcript level.
• how: The inhibitors TC-I-15 and obtustatin were tested in HUVECs using the same THPs (Fig 3a).

SUMMARY

Inhibition of α2β1 using the monoclonal antibody 6F1 or inhibition . . .

 



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