The effects of metformin in the treatment of osteoarthritis: current perspectives

HIGHLIGHTS

• who: August and collaborators from the Institut National de la Santé et de la Recherche Médicale (INSERM), France University of Dundee, United Kingdom have published the paper: The effects of metformin in the treatment of osteoarthritis: Current perspectives, in the Journal: (JOURNAL)
• what: Despite many efforts, there is still a lack of effective treatment for osteoarthritis, and the main objective of treatment is to reduce pain and slow down disease progression (Taruc-Uy and Lynch, 2013). This study proposes that metformin inhibits the ATP6AP1 protein of the lysosomal V-ATPase complex by binding to . . .
  

   

  

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