The effects of sirolimus and magnesium on primary human coronary endothelial cells: an in vitro study

HIGHLIGHTS

  • who: Giorgia Fedele and collaborators from the Department of Biomedical and Clinical Sciences, Universitu00e0 di Milano, Milano, Italy have published the research: The Effects of Sirolimus and Magnesium on Primary Human Coronary Endothelial Cells: An In Vitro Study, in the Journal: (JOURNAL)
  • what: The authors focused on Zonula Occludens 1 (ZO-1), a member of the tight junction family, and Vascular Endothelial Cadherin (VE-CAD), a member of the adherens junction family. The authors show that even a modest increase of extracellular Mg (3 mM) reduces the amounts of VCAM-1 and P-SEL, typically . . .

     

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