The effects of the levosimendan metabolites or-1855 and or-1896 on endothelial pro-inflammatory responses

HIGHLIGHTS

  • who: Hannah Kipka and colleagues from the ctoral Program Clinical Pharmacy, University Hospital, LMU Munich, Munich, Germany have published the paper: The Effects of the Levosimendan Metabolites OR-1855 and OR-1896 on Endothelial Pro-Inflammatory Responses, in the Journal: Biomedicines 2023, x of /2023/
  • what: The authors thus investigated the impact of the metabolites OR-1896 and OR-1855 processes in vitro. The authors show that the levosimendan metabolites OR-1855 and OR-1896, in contrast to levosimendan, do not affect endothelial inflammatory adhesion molecule expression but cytokine-induced MAPK activation leading to cellular . . .

     

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