The ejc disassembly factor pym is an intrinsically disordered protein and forms a fuzzy complex with rna

HIGHLIGHTS

  • who: RNA et al. from the York University, Canada have published the article: The EJC disassembly factor PYM is an intrinsically disordered protein and forms a fuzzy complex with RNA, in the Journal: (JOURNAL)
  • what: The authors determine the structure of PYM1-160 in solution and show that the protein is predominantly disordered, but tends to adopt u03b2-sheet-like structures in the first 60 amino_acids of the N-terminal domain and forms a more stable helical structure in the region 67-86. Using gel-mobility assays and NMR chemicalshift perturbation (CSP) data, the authors . . .

     

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