The emergence of up and down states in cortical networks

HIGHLIGHTS

• who: David Holcman et al. from the Weizmann Institute Superieure, Paris, France have published the article: The Emergence of Up and Down States in Cortical Networks, in the Journal: (JOURNAL)
• what: The model reveals that when the total synaptic connection strength exceeds a certain threshold the phase space of the dynamical system contains two attractors interpreted as Up and Down states. The authors propose here to investigate the role of the spontaneous activity in the generation of the Up and Down state transitions using a modeling approach. The authors demonstrate that in a sufficiently interconnected . . .
  

   

  

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