HIGHLIGHTS
- who: Nathalie Bonnefoy from the de Montpellier, Institut Ru00e9gional du Cancer de Montpellier, Montpellier, France Tulane University, United States have published the Article: The Emerging Role of the IL-17B/IL-17RB Pathway in Cancer, in the Journal: (JOURNAL)
SUMMARY
In each study, inhibition of the IL-17B/IL-17RB axis by downregulating receptor expression in tumor cells or by using neutralizing anti-IL-17RB antibodies restored chemosensitivity in_vitro and in_vivo. Similarly, IL-17B or IL-17RB silencing in cancer cells or treatment with antibodies targeting IL-17RB reduced proliferation of MDA-MB361 . . .
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