HIGHLIGHTS
- who: COPYRIGHT and colleagues from the Shenzhen University, China have published the article: The emerging roles of PHOSPHO1 and its regulated phospholipid homeostasis in metabolic disorders, in the Journal: (JOURNAL)
- how: These results indicated that Asp123 and Asp43 of motif I might be the active enzymatic sites of PHOSPHO1 protein in catalyzing different substrates (Stewart et_al 2003).
- future: Future studies utilizing tissue-specific PHOSPHO1 knockout and transgenic mouse models could dissect the role of PHOSPHO1 in metabolically active tissues and organs such as adipose_tissue liver and skeletal muscle.
SUMMARY
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