The enigma of substrate recognition and catalytic efficiency of ape1-like enzymes

HIGHLIGHTS

  • who: Olga S. Fedorova and Nikita A. Kuznetsov from the Institute of Chemical and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, National Taiwan Ocean University have published the article: The Enigma of Substrate Recognition and Catalytic Efficiency of APE1-Like Enzymes, in the Journal: (JOURNAL)
  • what: The aim of the study was to compare the kinetics of conformational changes of three homologous APE1-like endonucleases (insect Drosophila melanogaster Rrp1, amphibian Xenopus laevis xAPE1, and fish Danio rerio zAPE1) during their interaction with various damaged DNA substrates. The authors compare properties of APE1 . . .

     

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