HIGHLIGHTS
- who: Sylvaine Renault from the Abbreviations ChIP: Chromatine immuno-precipitation have published the article: The epigenetic regulation of HsMar1, a human DNA transposon, in the Journal: (JOURNAL)
- what: The authors show that HsMar1 excision is blocked in HeLa cells whereas CHO cells are competent to promote HsMar1 excision. The authors demonstrate that novo HsMar1 insertions in HeLa cells (human) undergo rapid silencing by cytosine methylation and apposition of H3K9me3 marks whereas novo HsMar1 insertions in CHO cells (hamster) are not repressed and enriched in H3K4me3 modifications. The authors describe how human DNA transposons are regulated . . .
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