HIGHLIGHTS
- who: Audrey Christine from the (UNIVERSITY) have published the research work: The equilibrium of tumor suppression: DUBs as active regulators of PTEN, in the Journal: (JOURNAL) of 16/Nov/2022
- future: These findings suggest that future studies should optimize the accurate stratification of deubiquitinase-targeted therapies for specific organs or tissues. Work is needed to precisely characterize the function/activity of the USP11-PTEN axis in DNA repair by the HR pathway to maintain genomic stability and suppress tumorigenesis.
SUMMARY
PTEN (phosphatase and tensin homolog deleted on chromosome 10) is one . . .
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