The erk5/nf-κb signaling pathway targets endometrial cancer proliferation and survival

HIGHLIGHTS

• who: Nora Diu00e9guez-Martu00ednez from the Autu00f2noma Barcelona (UAB), Barcelona, Spain Yu00fczu00fcncu00fc Yu0131l University, Van, Turkey have published the paper: The ERK5/NF-u03baB signaling pathway targets endometrial cancer proliferation and survival, in the Journal: (JOURNAL)
• what: The authors show that ERK5 inhibition or silencing decreased EGF-induced EC cell proliferation and that genetic deletion of MEK5 resulted in EC impaired proliferation and reduced tumor growth capacity in nude mice. The authors propose the ERK5/NF-u03baB axis as new target for EC treatment. The authors have investigated for the first time the role of . . .
  

   

  

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