HIGHLIGHTS
- who: Chiara Cassioli from the Department of Life Sciences, University of Siena, Siena, Italy have published the research work: The Expanding Arsenal of Cytotoxic T Cells, in the Journal: (JOURNAL)
SUMMARY
The multivesicular structure of LGs is generated through the invagination of the membrane of early endosomes (EE), the sorting hub for proteins endocytosed at the cell surface, which accounts for the identification of plasma_membrane-associated proteins such as T_cell receptors (TCRs) and integrins in the multivesicular cortex and highlights the endolysosomal origin of these organelles. A possible mechanism is suggested by the . . .
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