The exploration of complement-resistance mechanisms of pathogenic gram-negative bacteria to support the development of novel therapeutics

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  • who: Marta K. Ruest and Jonathan J. Dennis from the Department of Biological Sciences, University of Alberta, Edmonton, AB T G , Canada have published the paper: The Exploration of Complement-Resistance Mechanisms of Pathogenic Gram-Negative Bacteria to Support the Development of Novel Therapeutics, in the Journal: Pathogens 2022, 931 of /2022/
  • what: Although the main objective of the complement system is to defend against pathogenic invaders, the response may also indirectly result in host cell damage. Since the authors propose the use of MAbs targeting complement-resistance factors of pathogens, it is worth noting . . .

     

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