The expression of cellular prion protein, prpc, favors ptau propagation and blocks nmdar signaling in primary cortical neurons

HIGHLIGHTS

  • who: Rafael Rivas-Santisteban and collaborators from the Centro de Investigaciu00f3n Biomu00e9dica en Red Enfermedades Neurodegenerativas (CiberNed), National Institute of Health III, Madrid, Spain Institute of Neuroscience (NeuroUB), University of Barcelona, AvJoan XXIII, Barcelona, Spain have published the research work: The Expression of Cellular Prion Protein, PrPC, Favors pTau Propagation and Blocks NMDAR Signaling in Primary Cortical Neurons, in the Journal: Cells 2023, 12, 283. of /2023/
  • what: The aim of this paper was to investigate the potential effects on the NMDAR function of proteins prone to aggregate in neurodegenerative diseases. Mice were handled, as . . .

     

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