The “extreme phenotype approach” applied to male breast cancer allows the identification of rare variants of atr as potential breast cancer susceptibility alleles

HIGHLIGHTS

• who: Geoffrey Bertolone and collaborators from the 231, Universitu00e9 de Bourgogne, Dijon, France Human DNA Damage Response Disorders Group, University of Sussex, Genome Damage and Stability Centre, Brighton have published the Article: The u201cextreme phenotype approachu201d applied to male breast cancer allows the identification of rare variants of ATR as potential breast cancer susceptibility alleles, in the Journal: (JOURNAL)
• what: Using a combination of ES, direct sequencing of ATR in a replication cohort and prospective screening, followed by functional investigations the authors report the identification of new candidate variants of ATR as predisposing to BC . . .
  

   

  

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