The false dawn of polygenic risk scores for human disease prediction

HIGHLIGHTS

  • who: Anthony F. Herzig and collaborators from the Université Paris Cité, Institut Imagine, Laboratoire Embryologie et Génétique des Malformations, Paris, France have published the research work: The False Dawn of Polygenic Risk Scores for Human Disease Prediction, in the Journal: (JOURNAL) of 26/06/2000

SUMMARY

    It was also discovered that an allele that confers risk for a disease could be protective against another disease such as where, for example, the DR15 antigen increases the risk of multiple_sclerosis (MS), but decreases the risk of type 1 diabetes or rheumatoid arthritis. Similarly . . .

     

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