The fanc/brca pathway releases replication blockades by eliminating dna interstrand cross-links

HIGHLIGHTS

  • who: Xavier Renaudin and Filippo Rosselli from the CNRS, Université Paris-Saclay, Gustave Roussy Institute, Villejuif, France have published the Article: The FANC/BRCA Pathway Releases Replication Blockades by Eliminating DNA Interstrand Cross-Links, in the Journal: Genes 2020, 11, 585 of /2020/
  • how: The first one based on several cellular biochemical and molecular approaches was proposed in its original version several years ago by Niedernhofer and collaborators .

SUMMARY

    Independent of its size, chemical structure and molecular weight, a DNA interstrand cross-link (ICL) has two direct consequences on the chemistry . . .

     

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