The fda-approved drug auranofin has a dual inhibitory effect on sars-cov-2 entry and nf-κb signaling

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  • who: Emmanuel Laplantine from the Universitu00e9s, Institut National de la Santu00e9 et de la Recherche Mu00e9dicale (INSERM, UMR1135), Centre National de la Recherche Scientifique (CNRS, ERL8255), Centre d`Immunologie et des Maladies Infectieuses CMI, Paris, France have published the research work: The FDA-approved drug Auranofin has a dual inhibitory effect on SARS-CoV-2 entry and NF-u03baB signaling, in the Journal: (JOURNAL) of October/21,/2022
  • what: Whereas this study showed that Auranofin has no obvious effect on the S/ACE2 interaction, it displayed a strong inhibitory effect on PLpro, which also interferes . . .

     

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