The first 100 nm inside the pre-synaptic terminal where calcium diffusion triggers vesicular release

HIGHLIGHTS

• who: David Holcman from the Department of Mathematics and Brain Research Center, University of British Columbia, Vancouver, BC, Canada, Group of have published the research work: The First 100 nm Inside the Pre-synaptic Terminal Where Calcium Diffusion Triggers Vesicular Release, in the Journal: (JOURNAL)
• what: The authors focus this review on this paradigm shift of analyzing the diffusion of calcium ions and in particular about the nano-metric relation between the organization of calcium channels and vesicles and how it shapes the release probability, synaptic transmission, asynchronous release, and short-term plasticity.
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