HIGHLIGHTS
- who: Sayuri Mototani et al. from the Faculty of Pharmaceutical Sciences, Teikyo University, Kaga, Itabashi, Tokyo, Japan have published the research: The First Convergent Synthesis of 23,23-Difluoro-25-hydroxyvitamin D3 and Its 24-Hydroxy Derivatives: Preliminary Assessment of Biological Activities, in the Journal: Molecules 2022, 27, 5352. of /2022/
- what: The authors report an efficient synthetic route for the 23 and its 24-hydroxylated analogues which are candidates for the CYP24A1 main metabolites of 5. During the ongoing vitamin D3 research, the authors focused on the vitamin D3 side-chain C23 position and . . .
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