The frontline antibiotic vancomycin induces a zinc starvation response in bacteria by binding to zn(ii)

HIGHLIGHTS

• who: Ashraf Zarkan from the DepartmentUniversity of have published the article: The frontline antibiotic vancomycin induces a zinc starvation response in bacteria by binding to Zn(II), in the Journal: Scientific Reports Scientific Reports
• what: The authors investigate this hypothesis and report that vancomycin indeed acts as a weak zinc chelator that is capable of inducing the activity of Zur-dependent zinc homeostasis mechanisms in a range of bacteria. The authors determine the binding affinity of vancomycin for Zn(II) and define a potential binding_site.
• how: The results were analysed using 7300 system . . .
  

   

  

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