The functional role of sequentially neuromodulated synaptic plasticity in behavioural learning

HIGHLIGHTS

  • who: Grace Wan Yu Ang and collaborators from the Cambridge, United Kingdom have published the paper: The functional role of sequentially neuromodulated synaptic plasticity in behavioural learning, in the Journal: (JOURNAL) of June/10,/2021
  • what: The work seeks to connect synaptic level changes to behaviour. Using experimental and computational means, the authors investigate the mechanisms through which neuromodulated-plasticity in the hippocampus influences reward learning. The authors show that the model captures the selective deficit in reversal learning caused by the optogenetic manipulation, and explains inter-individual variability in performance. In contrast, neuromodulator amplitudes . . .

     

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