The functionality of apigenin as a novel cardioprotective nutraceutical with emphasize on regulating cardiac micro rnas

HIGHLIGHTS

  • who: Apigenin and colleagues from the Tabriz University of Medical Sciences, Tabriz, Iran have published the paper: The Functionality of Apigenin as a Novel Cardioprotective Nutraceutical with Emphasize on Regulating Cardiac Micro RNAs, in the Journal: (JOURNAL)
  • what: The findings of the current review study revealed that apigenin is capable of regulating different miRNAs, including miR-103, miR122-5p, miR-15b, miR-155, and miR-33, which in turn modifies several signaling pathways, inhibits cardiac apoptosis, suppresses oxidative stress, alters autophagic flux, decreases coronary lipotoxicity and improve cholesterol efflux via affecting the expression of ABCA1 . . .

     

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