HIGHLIGHTS
- who: Anna Sanchez and colleagues from the Department of Oncogenetics, Centre Perrin, CBRV, Clermont-Ferrand, France have published the paper: The Functions of the Demethylase JMJD3 in Cancer, in the Journal: (JOURNAL)
- what: In this review the authors focused on post-translational changes in histones and more particularly the tri methylation of lysine from histone 3 (H3K27me3) mark a repressive epigenetic mark often under- or overexpressed in a wide range of cancers.
- how: In 2012 the same observation was made after the catalytic activity of JMJD3 was inhibited by GSK-J1.
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.