The gp91phox component of nadph oxidase is not the voltage-gated proton channel in phagocytes, but it helps*

HIGHLIGHTS

• who: Thomas E. DeCoursey from the (UNIVERSITY) have published the research: The gp91phox Component of NADPH Oxidase Is Not the Voltage-gated Proton Channel in Phagocytes, but It Helps*, in the Journal: (JOURNAL) of June/25,/2001
• what: Although it is possible that gp91phox itself modulates H⫹ channels, the authors propose that these modulations of H⫹ channel function occur only in the presence of a functioning NADPH oxidase complex.

SUMMARY

To test whether gp91phox functions as a proton channel, the authors studied Hⴙ currents in granulocytes from X-linked chronic granulomatous . . .

 



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