HIGHLIGHTS
- who: Gerd Bendas from the (UNIVERSITY) have published the article: The GPIb-IX complex on platelets: insight into its novel physiological functions affecting immune surveillance, hepatic thrombopoietin generation, platelet clearance and its relevance for cancer development and metastasis, in the Journal: (JOURNAL)
- what: In the last years, eminent progress has been made in the understanding of the physiological function of the GPIbIX complex.
- how: This review describes the concepts of GPIb-IX signal mechanotransduction and GPIb-IX as thrombin receptor. In 1986 a model was proposed in which thrombin binds to GPIb providing . . .
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