The hapstr2 retrogene buffers stress signaling and resilience in mammals

HIGHLIGHTS

• who: David R. Amici from the (UNIVERSITY) have published the research: The HAPSTR2 retrogene buffers stress signaling and resilience in mammals, in the Journal: (JOURNAL) of 10/06/2022
• what: More broadly, the authors reason that the weaker HAPSTR2::HUWE1 interaction enables a system whereby competing HAPSTR1 regulatory mechanisms remain independent and energy efficient.
• future: The authors found no evidence for sexspecificity in HAPSTR2 expression but future studies in_vivo will be required to investigate sex-specific consequences for physiology. Residual expression of HAPSTR2 in some neural or germline cancers (and de novo expression . . .
  

   

  

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