The hepatitis c virus ns3 protein: a model rna helicase and potential drug target

HIGHLIGHTS

  • who: Curr. Issues Mol. Biol. et al. from the Department of Biochemistry and Molecular Biology, New York Medical College, Valhalla, NY, USA have published the research work: The Hepatitis C Virus NS3 Protein: A Model RNA Helicase and Potential Drug Target, in the Journal: (JOURNAL)
  • what: In the model shown in Fig 3, Arg467 and Arg464 are nearest the phosphates of ATP. This model has been applied to HCV helicase by Levin et_al (Levin et_al, 2003), who recently observed that HCV helicase has a higher affinity for a partially duplex DNA substrate with 3`-ssDNA . . .

     

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