The hexokinase “hkdc1” interaction with the mitochondria is essential for liver cancer progression

HIGHLIGHTS

• who: Md. Wasim Khan from the Animal studies All animal experiments were approved by the University of Illinois at Chicago Institutional Animal Care and Use Committee, as required by United States Animal Welfare Act, and the NIH`s policyFor Fig. D, mice were either fed low fat, cholesterol, and fructose (LFCF, Control, Cat #, ) or the high fat, cholesterol, and fructose (HFCF, NASH diet, Cat #, Research diets, Inc) diets for , weeks. DEN model. For diethylnitrosamine (DEN)-induced hepatocarcinogenesis, floxed mice were crossed with Albumin-Cre mice (Jackson Lab, Stock No:, ) [28] to create a liver-specific , knockout mouse . . .
  

   

  

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